Aligning digital development projects with regional and national management information systems is a key component of moving to scale. District Health Information Software version 2 (DHIS 2) is a free, web-based, and open source software tool used at scale in a dozen countries to support the collection and use of health indicators. Key components of scale include: adaptability through use of global standards; interoperability with apps, portals and other information systems; and “Academies” dedicated to supporting the user community. For more information, visit www.dhis2.org.